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Feb 13 2008, 08:39
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Salvia Kenner ![]() Gruppe: Members Beiträge: 121 Mitglied seit: 13.Oct 2006 Alter: 52 Aus: California USA |
Much to my disgust I read about Germany proposing Salvia be banned: I'll bet some German Journalist demanded that this harmless medicinal plant be banned as a dangerous addictive hallucinogen. Don't bother with the FACTS: Ban it before research can be conducted into it's medicinal value.
Germany should learn from the States of California and Maine how to treat it citizens. California and Maine admit there is no ongoing public health hazards associated with this plant: no record of emergency room visits, of overdoses, of public addictive behavior - like Salvia addicts mugging old ladies to get a 'fix'. There are considerably more repercussions to arresting gardeners and taxing the remaining taxpayers MORE to house the naughty gardeners for a long time - economic and social repercussions! Read this Please: http://sagewisdom.org/lettertocsa.pdf It has come to my attention that there have been a lot of ‘scare tactic’ stories on TV, and radio, and in the newspaper, about the evils and dangers of our kids smoking a hallucinogenic herb. I have seen articles stating that this is the most dangerous drug to come along since marijuana, and those claiming it is addictive. When did German legislators start believing everything they see on television? Television isn’t in it for the truth, television is in it for big ratings. “Salvia Madness” looks like a tired rerun of “Reefer Madness” to me, and media sensationalism is a poor excuse for making felons out of tens of thousands of Law abiding Germans. I have seen mostly lies and disinformation being publicly spread about this misunderstood plant, and it’s time for the truth to be told about it. I began researching this interesting and lovely plant over three and a half years ago, and in three years I have come to be considered one of California’s leading researchers into the botany of this unique plant. The truth is, when used by responsible adults in the privacy of their own homes, there is absolutely no harm in this plant. In fact, this plant shows great potential for producing many NEW medicines, including: painkillers, new treatments for depression, diarrhea, mood disorders, Alzheimer’s disease, and a possible treatment for cocaine addiction. This plant is the world’s most powerful, natural, and safest aphrodisiac. This plant is also very ornamental and is grown by thousands of Germans: as well as being used as a religious sacrament by many. There are many valid arguments against making Salvia Divinorum a Schedule I substance in Germany: • Regular gardeners should not be made into felons. Even the state of Tennessee, in their Public Chapter Number 700, provided that “It would not be a criminal offense to possess, plant, cultivate, grow, or harvest Salvia divinorum for aesthetic, landscaping, or decorative purposes. Also, this amendment does not apply to any dosage that is legally obtainable from a retail establishment without a prescription when it is recognized by the FDA as a homeopathic drug.” Likewise, the states of Maine, California, and Georgia do not prohibit gardeners’ from landscaping with this plant. • This plant has great potential therapeutic value. Recent research has indicated compounds in this plant may be the key to understanding and finally breaking the cycle of cocaine addiction. To attempt to ban the plant, in the name of the war on drugs, that could possibly be the means to ending the need for some of the war on drugs in the first place, would be the height of well meaning ignorance. If you ban further research with these plants, that might be key research in determining how to block the molecular pathways that cause cocaine addiction, you have only made the world a worse place to live in, and HINDERED yourselves in the war on drugs. • This Plant is Non-Addictive. No one has ever died of an overdose. It is a natural healing sacrament with a long history of being used by spiritual seekers in religious settings. There should not be a law banning adults from choosing to use this plant as a religious sacrament. Just because you do not know anyone who goes to O Centro Espirita Beneficiente Uniao Do Vegetal (UDV) does not mean it is not a church. "The Religious Freedom Restoration Act was adopted by Congress to ensure that the government does not interfere with religious practices absent a compelling justification" • There is a team of Doctors at the University of Iowa, under Dr. Thomas Prisinzano, with funding from the National Institute on Drug Abuse (NIDA), that are now studying salvinorin A and attempting to develop derivatives that could be useful for treating methamphetamine and cocaine dependence. • The American Civil Liberties Union, with their Center for Cognitive Liberty and Ethics, has published a PDF Pamphlet explaining why Salvia Divinorum is not suitable for scheduling. http://www.cognitiveliberty.org/pdf/salvia_dea.pdf • Germany does not have the millions or billions of extra enforcement funds to throw away by making citizens into criminals. • Germany does not have the thousands of extra jail cells to put all these proposed new felons in. Germany will need to build new prisons to relieve overcrowding. • For every German incarcerated for growing plants: Germany loses a taxpayer and must spend more Tax Funds to house and feed them in punishment. You reduce the available income to the government while requiring an increase of funds expenditures at the same time: a Double hit to the German Economy every time an innocent gardener is persecuted for growing harmless plants in this latest "Witch Hunt" ... • Tell those Nazis not to attempt to legislate their Christian morals onto your pagan lifestyle, and to find more constructive ways to spend public law enforcement funds: Like spending it to catch Rapists and Murderers maybe? Tell your lawmakers that Germany NEEDS Safer Anesthetics and new treatments for Alzheimer's and depression and that scare stories are about to make you BAN a Cure for Addictions! I'll get down off my soapbox now but advise you ALL to write your legislative representatives protesting the loss of your liberties one at a time! Speak up about this freedom: let your voices be collectively heard or shut up and let them drown you out with their false fears ... Grrrrrrrrrrrr I'm so pissed off about this! Does Germany have no due process to prevent religious persecution or other abuse of official power? Is there no reasonable argument to the self destructive economic policy of warring on Germany's own citizens over a HARMLESS Plant? Carl McCall - Salvia Researcher. Der Beitrag wurde bearbeitet von Sea Mac am Feb 13 2008, 08:53 Uhr. -------------------- Sea Mac
My Little Garden :) It's Hummertime! :lol: The Lucky Leprechaun :D Growing Salvia Divinorum for Seeds ;) |
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Feb 13 2008, 08:58
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#2
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Salvianaut ![]() ![]() ![]() ![]() Gruppe: V.I.P. Beiträge: 1.250 Mitglied seit: 14.May 2007 Alter: 25 |
QUOTE(Sea Mac @ Feb 13 2008, 08:40) I think there's no one on this board who doesn't share your opinions. You run into open doors here. Actually there were not sooo much media scare tactics here. The decision was made within the responsible governmental groups. The reason which were given are very unclear, e.g. they wrote half a year ago an open response to a request in which they stated that they have no knowlegde whatsoever about the widespread of Salvia divinorum use in Germany; it basically said "we have no idea and don't care a lot for now". Nevertheless they now tell it's beginning to widespread, that they are possibilities that it may causes psychosis or other "medicinal problems". They haven't presented (or at least) cited yet any scientific proof for their claims. Not even a selfmade statistic. Nothing. Some guys here call it "the evidence that Germany is not a Rechtsstaat anymore"... -------------------- Pflichtlektüre für neue SC-Member:
Kampfzwerg und der wilde Büffel - Eine Komödie in einem Akt - psychoplant.bplaced.net ist leider vom Netz :( Vegetarier? Kann man die essen? QUOTE(slim @ Jan 10 2008) |
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Feb 13 2008, 12:33
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![]() Salvianaut ![]() ![]() ![]() ![]() Gruppe: Members Beiträge: 822 Mitglied seit: 25.Jun 2007 Alter: 26 |
Yep, nothing to do with TV here. Even our thread gathering newspaper articles about the plant is rather empty.
Letters have already been written at least on the open platform abgeordnetenwatch, where members of the Bundestag answer questions. As of now querists have only been pointed to the «kleine Anfrage der Grünen» (small survey of the green party) Amalgam mentioned, where the only information to be found is that there was nothing known about physical, mental or social harm. When asked about why a law is passed on behalf of the lack of knowledge, the answer referred to the conclusions of the medical committee, which was summoned for this case. Still no evidence has been produced, though it would be mandatory for the german equivalent of your schedule I. Sorry for my english, this topic clearly exceeds my vocabulary :/ Glass Der Beitrag wurde bearbeitet von Glassmoon am Feb 13 2008, 18:02 Uhr. -------------------- |
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Feb 13 2008, 15:00
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Salvia Kenner ![]() Gruppe: Members Beiträge: 101 Mitglied seit: 16.Sep 2007 Alter: 19 |
The problem is that the pharmaceutical industry has more influence on the government (through lobbyists) than the citizens whose rights are restricted.
They don't care about the additional costs because the taxpayers pay them at last... -------------------- "Out of chaos, find simplicity, From discord, find harmony." - Bruce Lee
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Feb 13 2008, 20:27
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#5
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Salvia Kenner ![]() Gruppe: Members Beiträge: 121 Mitglied seit: 13.Oct 2006 Alter: 52 Aus: California USA |
QUOTE(Glassmoon @ Feb 13 2008, 04:34) Yep, nothing to do with TV here. Even our thread gathering newspaper articles about the plant is rather empty. Letters have already been written at least on the open platform abgeordnetenwatch, where members of the Bundestag answer questions. As of now querists have only been pointed to the «kleine Anfrage der Grünen» (small survey of the green party) Amalgam mentioned, where the only information to be found is that there was nothing known about physical, mental or social harm. When asked about why a law is passed on behalf of the lack of knowledge, the answer referred to the conclusions of the medical committee, which was summoned for this case. Still no evidence has been produced, though it would be mandatory for the german equivalent of your schedule I. Sorry for my english, this topic clearly exceeds my vocabulary :/ Glass Your English is understandable: I couldn't have posted that rant in German. I was hoping for some feedback - and I was also hoping to learn a little more about the German process for law making. I really wanted to title it "TV tells us Illinois Folks what Laws to make!" Since that is apparently what was what happened. TV Scared Ignorant Legislators in Illinois by telling them it was an addictive hallucinogen getting the grade school kids "Hooked" and they promptly Declared it addictive and made it a Felony WITHOUT Doing any research! Anyone that has RESEARCHED this Plant KNOWS It has NO Addictive potential and it is VERY Plain that Illinois Legislators are not capable of doing ANY research beyond TV sound bites with no Factual Basis! I AM extremely pleased that Germany will have to PROVE this plant is Dangerous before banning it. The research is VERY Promising for many new medicines to come from this plant and I am going to make sure you people in this forum have enough facts to scream the ignorant fears down. All I ask is for Salvia to have her fair day in court. Let the Government try to prove harm from this Non-Toxic Plant! Let the Government try to deny that any useful medicines can come from this plant! It Can be proved otherwise! What the German Government needs to realize is that this is an "Adults Only" substance and that restricting sales to Minors is wholly appropriate - but NOT to make criminals out of Law Abiding German gardeners without justification. Here in California salvia activist activities prevented the California Legislators from making it a Felony in the last year - I myself WROTE Letters Publicly opposing AB259 as it was originally written! Last year Assemblyman Adams Introduced Assembly Bill AB259 proposing that everyone that touches that plant be declared a dangerous felon. A public outcry followed and the bill did not pass committee but a reconsideration was granted to try again. I wrote this Letter: http://members.cox.net/sageseeds/ab259.html and Mailed it on Quality Resume paper by certified Mail. I was listed as one of the "Seven Private Citizens" officially opposed to AB259. And then a Wonderful thing happened: the assemblyman that sponsored the original bill READ the opposition Letters AND DID some RESEARCH! He realized that this ISN'T a Dangerous plant and rewrote the text of AB259: "It shall be a Misdemeanor to provide Salvia to someone under 18". That passed committee unopposed and is well on it's way to being Section 379 of the California penal code! Any State that has Examined the evidence has concluded this is NOT a Dangerous addictive plant and can find no evidence for any public health hazards associated with it. But a Few States have passed exactly the Laws the TV set TOLD Them To! Advocacy has stopped wrongful legislation from being passed in a half dozen states here in the US and has proved that when concerned citizens speak up the justification for making gardeners felons disappears. If no one speaks out then the TV campaigns its sound bites unopposed and does grave economic damage by jailing thousands of innocent gardeners! I want Germany's laws to follow the states of Maine and California and NOT to follow the lead of the retards in Illinois - where TV Sound bites are all that are needed to pass unjust laws! So, pardon the aggressive title on this topic: I just wanted to be SURE that everyone spoke up! I will be glad to provide links to the ongoing research so you have knowledge to fight ignorance with! Der Beitrag wurde bearbeitet von Sea Mac am Feb 13 2008, 20:30 Uhr. -------------------- Sea Mac
My Little Garden :) It's Hummertime! :lol: The Lucky Leprechaun :D Growing Salvia Divinorum for Seeds ;) |
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Feb 13 2008, 20:48
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![]() Salvia Kenner ![]() Gruppe: Members Beiträge: 230 Mitglied seit: 10.Jan 2007 Alter: 23 |
QUOTE(Sea Mac @ Feb 13 2008, 20:28) I AM extremely pleased that Germany will have to PROVE this plant is Dangerous before banning it. The theory says so but in fact there has no research been done as far as i know. This friday the Bundesrat ist about to finaly decide if Salvia Divinorum (the Plant and Parts of the Plant, NOT Salvinorin) is declared illegal. The Bundestag already did and i don't see why the Bundesrat should turn his mind. This sucks. -------------------- |
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Feb 13 2008, 22:31
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Salvia Kenner ![]() Gruppe: Members Beiträge: 121 Mitglied seit: 13.Oct 2006 Alter: 52 Aus: California USA |
QUOTE(horst2k5 @ Feb 13 2008, 12:49) QUOTE(Sea Mac @ Feb 13 2008, 20:28) I AM extremely pleased that Germany will have to PROVE this plant is Dangerous before banning it. The theory says so but in fact there has no research been done as far as i know. This friday the Bundesrat ist about to finaly decide if Salvia Divinorum (the Plant and Parts of the Plant, NOT Salvinorin) is declared illegal. The Bundestag already did and i don't see why the Bundesrat should turn his mind. This sucks. So: in the name of German fair-mindedness they announce Jan 23rd that they will ban something - allow no public comment to be submitted - and by Feb 15th have it declared illegal with nothing you can do about it? The evidence that Germany is not a Rechtsstaat anymore is overwhelming: you poor people live in a dictatorship run by committees - and the committees flaunt your powerlessness over them by stealing Germans personal liberties one at a time under your very public noses! How about this Angle: you form a Legally incorporated "Church of the Green Sacrament" TODAY before they legally declare this plant to be an offense against God - and fight them under the freedom accorded to spiritual practices? Our could your legislators legally ban, say, any German from Worshiping at the Church of England just because it offended them? Does Germany even PRETEND to have freedom of religious practices: the way America does? How can you prevent German committee dictators from banning your spiritual sacraments ESPECIALLY as they cannot prove them harmful? Why is there no public say on what laws are made by those committees? What is to prevent them from declaring some thing ELSE they are afraid of to be illegal next: say, like the Jews? How much further behind can the return of the Concentration Camp be if it only takes 3 weeks for "Committee Members" to make up and ram through into law unpopular laws: with no comments allowed by the people? "We say all gardeners of this Plant are now all felons!" "And YOU Have no say about what we say: WE are the Decider's!" I don't see that as the actions of a "Free Country" - I see you as only having ONE Freedom Left: the Freedom to conform to what your "Government" mandates, or the Freedom to go to Jail for not marching in lockstep with your fellow slaves! "THEY" are in power now and there is no way they will EVER give deciding power BACK to you! And you can't make them ha-ha-ha: you have to obey their every whim! I'm 3 times more pissed off now than I was when I began this dialog. I want to help - Make me the founder of your church or something: so if they extradite me I'll give them a piece of my mind! (A Very little piece: I don't have much left!) Look for ANY loophole - like a Church or a Research Institute - to found today: so you can FORCE the issue into a hearing or court! If you can't: you must resign to live happily with your ONE Freedom left! Der Beitrag wurde bearbeitet von Sea Mac am Feb 13 2008, 22:43 Uhr. -------------------- Sea Mac
My Little Garden :) It's Hummertime! :lol: The Lucky Leprechaun :D Growing Salvia Divinorum for Seeds ;) |
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Feb 13 2008, 22:34
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![]() Salvia Fan ![]() ![]() Gruppe: Members Beiträge: 341 Mitglied seit: 26.Aug 2007 Alter: 22 |
QUOTE All I ask is for Salvia to have her fair day in court. Let the Government try to prove harm from this Non-Toxic Plant! Let the Government try to deny that any useful medicines can come from this plant! It Can be proved otherwise! What the German Government needs to realize is that this is an "Adults Only" substance and that restricting sales to Minors is wholly appropriate - but NOT to make criminals out of Law Abiding German gardeners without justification. The Paragraph wich is used(abused - Addiction possible or - big abuse and danger for the health Someone else said it, there is a Committee(Pharma community, Physicians community and animal physician community) which speaks to some Members of the goverment. To adopt the Law it's enough when the committee sais it' dangerous, facts are not necessairy. But there is a chance to sue against that after it is committed, but before not. -------------------- o
L _/ OL This is Schäuble. Copy Schäuble into your signature to help him on his way to Überwachungsstaat. |
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Werbung:
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![]() Werbefachmann ;-) ![]() ![]() ![]() ![]() ![]() Gruppe: Sponsoren Beiträge: n Mitglied seit: 20.Dez 2006 Alter: 0 |
-------------------- Hinweis: Bitte die jeweilige Gesetzgebung in deinem Land beachten! "All advertising advertises advertising." ~ Marshall McLuhan |
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Feb 13 2008, 23:22
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![]() Salvia Kenner ![]() Gruppe: Members Beiträge: 230 Mitglied seit: 10.Jan 2007 Alter: 23 |
There is not much doubt that s.d. will be illegal by the next week but it is another thing how the judges will use this. There is a realistic chance that they will recognize the lack off reasons in the illegalization of s.d.. This whole process has happend almost covered from the public eye. I don't think this is an irreversible one. Someday there will be scientifical studies that proof s.d. is a drug with a minimum of risk when used with responsibility and even those blinded politicians will perceive it .. i hope.
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Feb 14 2008, 00:07
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#10
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Salvia Kenner ![]() Gruppe: Members Beiträge: 121 Mitglied seit: 13.Oct 2006 Alter: 52 Aus: California USA |
QUOTE(horst2k5 @ Feb 13 2008, 12:49) QUOTE(Sea Mac @ Feb 13 2008, 20:28) I AM extremely pleased that Germany will have to PROVE this plant is Dangerous before banning it. The theory says so but in fact there has no research been done as far as i know. Nonsense! LOTS of research has been done - in English! Shake This Printed out sheaf of FACTS and Research in their faces on Friday and say "Here are the Facts you PURPOSELY IGNORED: Your 'medical committee' of lobbyist hand picked stooges Could not possibly have had time to review all this research in the 2 weeks you've been at this! Show us the 'research' and the credentials of your secret panel of experts!" I've found a LOT of research over at http://sagewisdom.org and you should print these and take to the 'hearing' (If there is one)! QUOTE Articles from Scientific Journals and Other Publications (Some of the following files are in PDF format. You'll need the Adobe Acrobat Reader to view them) The Botany of Salvia divinorum (Labiatae) by Reisfield AS. SIDA 15: 349-366 (1993). This web-optimized version of Reisfield's paper includes lots of great photos. Salvia divinorum and Salvinorin A: New Pharmacologic Findings. by Daniel Siebert. Journal of Ethnopharmacology. 43: 53–56 (1994). This paper is in PDF format. Localization of Salvinorin A and Related Compounds in Glandular Trichomes of the Psychoactive Sage, Salvia divinorum. by Daniel Siebert. Annals of Botany 93(6): 763–771 (2004). This paper is in PDF format.[/url] High Performance Liquid Chromatographic Quantification of Salvinorin A from Tissues of Salvia divinorum Epling & Játiva-M. by Gruber JW, Siebert DJ, Der Marderosian AH, and Hock RS. Phytochemical Analysis 10(1):22–25 (1999). Salvinorin A: A Potent Naturally Occurring Nonnitrogenous Kappa Opioid Selective Agonist. by Roth BL, Baner K, Westkaemper R, Siebert D, Rice KC, Steinberg S, Ernsberger P, and Rothman RB. PNAS. 99(18): 11934–11939 (2002). This document is in PDF format. Supporting information: table 3, table 4, table 5. Salvinorin A, an Active Component of the Hallucinogenic Sage Salvia divinorum, is a Highly Efficacious Kappa Opioid Receptor Agonist: Structural and Functional Considerations. by Chavkin C, Sud S, Jin W, Stewart J, Zjawiony JK, Siebert DJ, Toth BA, Hufeisen SJ, and Roth BL. The Journal of Pharmacology and Experimental Therapeutics. 308(3): 1197–1203 (2004). This document is in PDF format. Comparison of Pharmacological Activities of Three Distinct Kappa-Ligands (Salvinorin A, TRK-820 and 3FLB) on opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. by Wang Y, Tang K, Inan S, Siebert DJ, Holzgrabe U, Lee DYW, Huang P, Li JG, Cowan A, and Liu-Chen LY. The Journal of Pharmacology And Experimental Therapeutics. 312(1): 220–230 (2005). 2-Methoxymethyl-Salvinorin B is a Potent Kappa Opioid Receptor Agonist with Longer-Lasting Action In Vivo than Salvinorin A. by Wang Y, Chen Y, Xu W, Lee DY, Ma Z, Rawls SM, Cowan A, Liu-Chen LY. The Journal of Pharmacology And Experimental Therapeutics. [Epub ahead of print December 18, 2007]. The Hallucinogenic Herb Salvia divinorum and Its Active Ingredient Salvinorin A Inhibit Enteric Cholinergic Transmission in the Guinea Pig Ileum. by Capasso R, Borrelli F, Capasso F, Siebert DJ, Stewart DJ, Zjawiony JK, Izzo AA. Neurogastroenterology and Motility. 18: 69–75 (2006). The Hallucinogenic Herb Salvia divinorum and Its Active Ingredient Salvinorin A Reduce Inflammation-Induced Hypermotility in Mice. by Capasso R, Borrelli F, Zjawiony J, Kutrzeba L, Aviello G, Sarnelli G, Capasso F, Izzo AA. Neurogastroenterology and Motility. [Epub ahead of print Sep 4, 2007]. Antinociceptive and Hypothermic Effects of Salvinorin A are Abolished in a Novel Strain of KOR-1 KO Mice. by Ansonoff MA, Zhang J, Czyzyk T, Rothman RB, Stewart J, Xu H, Zjwiony J, Siebert DJ, Yang F, Roth BL, Pintar JE. The Journal of Pharmacology and Experimental Therapeutics. 318(2): 641-648 (2006). Daniel Siebert Speaks… Interviewed by Will Beifuss. The Entheogen Review. Vol. 8 No. 3, Autumn 1999. The History of the First Salvia divinorum Plants Cultivated Outside of Mexico. by Daniel Siebert. The Entheogen Review. Vol. 12 No. 4, Winter 2003. Salvinorin A: The ‘Magic Mint’ Hallucinogen Finds a Molecular Target in the Kappa Opioid Receptor. by Sheffler DJ and Roth BL. Trends in Pharmacological Sciences. Vol.24 No.3 March 2003. This review article is in PDF format. Salvinorin A: A Novel and Highly Selective Kappa-Opioid Receptor Agonist. by Yan F and Roth BL. Life Sciences. Vol.75 No.22 (2004). This review article is in PDF format. Salvinorin A: From Natural Product to Human Therapeutics. by Vortherms TA and Roth BL. Molecular Interventions. Vol.6 No.5 (2006). This review article is in PDF format. Differential Helical Orientations Among Related G Protein-Coupled Receptors Provide a Novel Mechanism for Selectivity: Studies with Salvinorin A and the Kappa-Opioid Receptor. by Vortherms TA, Mosier PD, Westkaemper RB, Roth BL. Journal of Biological Chemistry. 282(5): 3146–3156 (2007). This paper is in PDF format. Acute Physiologic and Chronic Histologic Changes in Rats and Mice Exposed to the Unique Hallucinogen Salvinorin A. by Mowry M, Mosher M, Briner W. Journal of Psychoactive Drugs. 35(3): 379–382 (2003). This paper is in PDF format. The Plant-Derived Hallucinogen, Salvinorin A, Produces Kappa-Opioid Agonist-like Discriminative Effects in Rhesus Monkeys. by Butelman E, Harris T, and Kreek MJ. Psychopharmacology (Berl). 172(2): 220–224 (2004). This paper is in PDF format. Effects of Salvinorin A, a Kappa-Opioid Hallucinogen, on a Neuroendocrine Biomarker Assay in Nonhuman Primates With High Kappa-Receptor Homology to Humans. by Butelman ER, Mandau M, Tidgewell K, Prisinzano TE, Yuferov V, Kreek MJ. Journal of Pharmacology and Experimental Therapeutics. 320(1): 300–306 (2007). This paper is in PDF format. A New Species of Salvia from Mexico. by Carl Epling and Carlos D. Játiva–M. Botanical Museum Leaflets Harvard University (1962). A New Mexican Psychotropic Drug From the Mint Family. by R. Gordon Wasson. Botanical Museum Leaflets Harvard University (1962). Notes on the Present Status of Ololiuhqui and the Other Hallucinogens of Mexico. by R. Gordon Wasson. Botanical Museum Leaflets Harvard University (1963). A Mazatec girl preparing Salvia divinorum leaves on a metate . Photo taken in 1962 by R. Gordon Wasson. In Search of the Magic Plant " Ska Maria Pastora " in the Mazatec Country. by Albert Hofmann. From: LSD: My Problem Child (1979). Salvinorin, A New trans -Neoclerodane Diterpene from Salvia divinorum (Labiatae). by Ortega A, Blount JF, Manchand PS. Journal of the Chemical Society Perkins Transactions I (1982). This document is in PDF format. Ethnopharmacology of Ska Maria Pastora ( Salvia divinorum , Epling and Játiva-M.). by L.J. Valdés J III, et al. Journal of Ethnopharmacology (1983). Etnofarmacologia di Ska Maria Pastora ( Salvia divinorum, Epling and Játiva-M.) An Italian translation of the above. Divinorin A, a Psychotropic Terpenoid, and Divinorin B from the Hallucinogenic Mexican Mint, Salvia divinorum . by L.J. Valdés III, et al. Journal of Organic Chemistry (1984). Loliolide from Salvia divinorum . by L.J. Valdés III. Journal of Natural Products (1986). Studies of Salvia divinorum (Lamiaceae), an Hallucinogenic Mint from the Sierra Mazateca in Oaxaca, Central Mexico. by L.J. Valdés III, et al. Economic Botany (1987). Salvia divinorum and the Unique Diterpene Hallucinogen, Salvinorin (Divinorin) A. by L.J. Valdés III. Journal of Psychoactive Drugs (1994). "Divinorin C," a New Neoclerodane Diterpene from a Bioactive TLC Fraction of Salvia divinorum. Lab notes from the desk of L. J. Valdés III. The Salvia divinorum Research and Information Center (2000). Salvinorin C, a New Neoclerodane Diterpene from a Bioactive Fraction of the Hallucinogenic Mexican Mint Salvia divinorum. by L.J. Valdés III, et al. Organic Letters (2001). The Early History of Salvia divinorum. by L. J. Valdés III. The Entheogen Review (2001) X(2): [73-75] Some photos of Salvia divinorum from the Sierra Mazateca. by L.J. Valdés III The Absolute Stereochemistry of Salvinorins. Also available in PDF format here. by Koreeda, M., et al. Chemistry Letters (1990). Kappa-Opioid Receptor-Mediated Effects of the Plant-Derived Hallucinogen, Salvinorin A, on Inverted Screen Performance in the Mouse. by Fantegrossi WE, Kugle KM, Valdιs LJ III, Koreeda M, Woods JH. Behavioural pharmacology. 16(8): 627-633 (2005). This document is in PDF format. Salvinorins D-F, New Neoclerodane Diterpenoids from Salvia divinorum, and an Improved Method for the Isolation of Salvinorin A. And supporting information. by Munro TA, Rizzacasa MA. Journal of Natural Products. 66(5): 703-705 (2003). These two documents are in PDF format. Divinatorins A-C, New Neoclerodane Diterpenoids from the Controlled Sage Salvia divinorum. And supporting information. by Bigham AK, Munro TA, Rizzacasa MA, Robins-Browne RM. Journal of Natural Products. 66(9): 1242-1244 (2003). These two documents are in PDF format. Studies Toward the Pharmacophore of Salvinorin A, a Potent Kappa Opioid Receptor Agonist. And supporting information.by Munro T, Rizzacasa M, Roth BL, Toth B, Yan F Journal of Medicinal Chemistry. 48(2): 345–348 (2005). This document is in PDF format. Autoxidation of Salvinorin A under Basic Conditions. And supporting information.by Munro T, Goetchius G, Roth BL, Vortherms T, Rizzacasa M. Journal of Organic Chemistry. 70(24): 10057-10061 (2005). This document is in PDF format. 8- epi -Salvinorin B: Crystal Structure and Affinity at the Kappa Opioid Receptor. by Munro TA, Duncan KK, Staples RJ, Xu W, Liu-Chen LY, Beguin C, Carlezon WA Jr, Cohen BM. Beilstein Journal of Organic Chemistry. Epub ahead of print (2007). This document is in PDF format. The Chemistry of Salvia divinorum. by Thomas Munro. PhD dissertation. This is a large (283 pages - 6.32 MB) document, in PDF format. Standard Protecting Groups Create Potent and Selective Kappa Opioids: Salvinorin B Alkoxymethyl Ethers by Munro TA, Duncan KK, Xu W, Wang Y, Liu-Chen LY, Carlezon WA Jr, Cohen BM, Beguin C. 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A Facile Method for the Preparation of Deuterium Labeled Salvinorin A: Synthesis of [2,2,2-<SUP>2</SUP>H<SUB>3</SUB>]-Salvinorin A by Kevin Tidgewell, Wayne W. Harding, Mark Schmidt, Kenneth G. Holden, Daryl J. Murry, and Thomas E. Prisinzano. Bioorganic and Medicinal Chemistry Letters. 14(20): 5099-5102 (2004). This document is in PDF format. Salvinicins A and B, New Neoclerodane Diterpenes from Salvia divinorum. by Harding WW, Tidgewell K, Schmidt M, Shah K, Dersch CM, Snyder J, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Organic Letters. 7(14): 3017–3020 (2005). This document is in PDF format. Neoclerodane Diterpenes as a Novel Scaffold for Mu Opioid Receptor Ligands. by Harding WW, Tidgewell K, Byrd N, Cobb H, Dersch CM, Butelman ER, Rothman RB, Prisinzano TE. Journal of Medicinal Chemistry. 48(15): 4765–4771 (2005). This document is in PDF format. An Opioid Agonist That Does Not Induce Mu-Opioid Receptor–Arrestin Interactions or Receptor Internalization. by Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM. Molecular Pharmacology. 71(2): 549–557 (2007). This document is in PDF format. Salvinorin A: Allosteric Interactions at the Mu-Opioid Receptor. by Rothman RB, Murphy DL, Xu H, Godin JA, Dersch CM, Partilla JS, Tidgewell K, Schmidt M, Prisinzano TE. Journal of Pharmacology and Experimental Therapeutics. 320(2): 801–810 (2007). This document is in PDF format. Determination of Salvinorin A in Body Fluids by High Performance Liquid Chromatography-Atmospheric Pressure Chemical Ionization. by Schmidt MS, Prisinzano TE, Tidgewell K, Harding W, Butelman ER, Kreek MJ, and Murry DJ. Journal of Chromatography. B. 818(2): 221–225 (2005). This document is in PDF format. Pharmacokinetics of the Plant-Derived Kappa-Opioid Hallucinogen Salvinorin A in Nonhuman Primates. by Schmidt MD, Schmidt MS, Butelman ER, Harding WW, Tidgewell K, Murry DJ, Kreek MJ, Prisinzano TE. Synapse. 58(3): 208–210 (2005). This document is in PDF format. Psychopharmacology of the Hallucinogenic Sage Salvia divinorum. by Prisinzano TE. Life Sciences. 78(5): 527-531 (2005). This document is in PDF format. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A. by Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Gilmour B, Navarro H, Rothman RB, Prisinzano TE. Journal of Natural Products. 69(1): 107–112 (2006). This document is in PDF format. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Selective Modification of the Furan Ring. by Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE. Bioorganic & Medicinal Chemistry Letters. 16(12): 3170–3174. This document is in PDF format. Synthesis of Salvinorin A Analogues as Opioid Receptor Probes. by Tidgewell K, Harding WW, Lozama A, Cobb H, Shah K, Kannan P, Dersch CM, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Journal of Natural Products. 69(6): 914–918 (2006). This document is in PDF format. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Preparation and Opioid Receptor Activity of Salvinicin Analogues. by Simpson DS, Katavic PL, Lozama A, Harding WW, Parrish D, Deschamps JR, Dersch CM, Partilla JS, Rothman RB, Navarro H, Prisinzano TE. Journal of Medicinal Chemistry. [ePublished ahead of print Jun 20, 2007]. This document is in PDF format. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Exploration of the 1-Position. by Holden KG, Tidgewell K, Marquam A, Rothman RB, Navarro H, Prisinzano TE. Bioorganic and Medicinal Chemistry Letters. . 17(22): 6111–6115 (2008). This document is in PDF format. Neo-clerodane Diterpenes from the Hallucinogenic Sage Salvia divinorum. And errata. by Shirota O, Nagamatsu K, Sekita S. Journal of Natural Products. 69(12): 1782–1786. (2006). This document is in PDF format. Asymmetric Synthesis of Salvinorin A, a Potent Kaapa Opioid Receptor Agonist. by Scheerer JR, Lawrence JF, Wang GC, Evans DA. Supporting information here (4 MB file). Journal of the American Chemical Society. [ePublished ahead of print June 30, 2007]. This document is in PDF format. Quantification of the Plant-Derived Hallucinogen Salvinorin A in Conventional and Non-Conventional Biological Fluids by gas chromatography/mass spectrometry after Salvia divinorum smoking. by Pichini S, Abanades S, Farre M, Pellegrini M, Marchei E, Pacifici R, Torre RD, and Zuccaro P. Rapid Communications in Mass Spectrometry. 19(12): 1649–1656 (2005). This paper is in PDF format. Synthesis and In Vitro Pharmacological Evaluation of Salvinorin A Analogues Modified at C(2). by Beguin C, Richards MR, Wang Y, Chen Y, Liu-Chen LY, Ma Z, Lee DY, Carlezon WA Jr, and Cohen BM. Bioorganic and Medicinal Chemistry Letters. 15(11): 2761–2765 (2005). This document is in PDF format. Synthesis and In Vitro Pharmacological Studies of New C(2) Modified Salvinorin A Analogues. by Lee DY, Karnati VV, He M, Liu-Chen LY, Kondareti L, Ma Z, Wang Y, Chen Y, Beguin C, Carlezon WA Jr, Cohen B. Bioorganic and Medicinal Chemistry Letters. 15(16): 3744–3747 (2005). This document is in PDF format. Synthesis and In Vitro Pharmacological Studies of C(4) Modified Salvinorin A Analogues. by Lee DY, He M, Kondaveti L, Liu-Chen LY, Ma Z, Wang Y, Chen Y, Li JG, Beguin C, Carlezon WA Jr, Cohen B. Bioorganic and Medicinal Chemistry Letters. Jul 25, 2005 [Epub ahead of print]. This document is in PDF format. New Neoclerodane Diterpenoids Isolated From the Leaves of Salvia divinorum and Their Binding Affinities for Human Kappa Opioid Receptors. by Lee DY, Ma Z, Liu-Chen LY, Wang Y, Chen Y, Carlezon WA Jr, Cohen B. Bioorganic and Medicinal Chemistry Letters. Aug 3, 2005 [Epub ahead of print]. This document is in PDF format. Synthesis and In Vitro Pharmacological Studies o |